Double Marker Test is an important test for pregnant females. The test is advised and done at Maurya Labs for pregnant females between 16 to 18 weeks of pregnancy. The test aims at screening for Down syndrome, trisomy 13, and trisomy 18 markers. Down Syndrome is a condition that affects the while child due to chromosomal disorder. Down syndrome is a genetic condition where a person has an extra copy of chromosome 21, or a part of it. This extra genetic material can lead to developmental delays, intellectual disability, and characteristic physical features.
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A Double Marker Test is a test used to identify whether the fetus has any chromosomal abnormalities. This test is crucial for detecting any neurological problems in the fetus, such as Down’s syndrome or Edward’s Syndrome.
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The Double Marker Test results are classified as screen positive and screen negative and are presented in the form of ratios. A ratio of 1:10 to 1:250 is termed ‘screen positive,’ which is highly dangerous for both the mother and the developing foetus. Whereas, a ratio of 1:1000 or above is termed ‘screen negative,’ which is a safe result that poses fewer risks.
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What does the Double Marker Test Measure ?
A double marker test basically screens the pregnant female for own syndrome, trisomy 13, and trisomy 18 markers. The test is important as in India an abortion can be allowed due to a medical condition only upto 24 weeks. In case the female shows high probability that the child may have Down Syndrome then the pregnancy can be aborted by 20th week.
Why should I do the Double Marker Test ?
It aids in determining whether the unborn child is at risk of developing a mental illness. It is mostly used to screen for Down syndrome. Trisomy 18, which causes mental retardation and serious birth abnormalities, can also be detected with the Double Marker Test. It's also useful for detecting Trisomy 21.
How is the Double Marker Test Done ?
The test is done at Maurya Labs using the blood sample. This test looks for two markers such as beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein A levels in the blood (PAPP-A). In a typical pregnancy, female fetuses will have 22 pairs of XX chromosomes, whereas male fetuses would have 22 pairs of XY chromosomes. When there is an aberration in chromosomes, this results in an abnormality.
Is NIPT and Double Marker test same?
NIPT (Non-Invasive Prenatal Screening Test) and Double Marker Test are different.
NIPT is a DNA test that uses maternal blood to screen for the most common fetal chromosomal defects, including trisomy 21 (Down syndrome), trisomy 18 (Edwards syndrome), and trisomy 13. (Patau syndrome).
LThe double marker test is a screening blood test for pregnancy. It is usually taken within 9 to 13 weeks. When a double marker test is used with an NT scan, it produces a result that uses a high risk or low risk for chromosomal abnormalities, particularly for Down syndrome or trisomies.
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Opposite Sadar Hospital, Azad Nagar,
Araria, Bihar - 854311
Mob : +91-92 34 34 4301
Power House Road, Near HP World,
Rajhata, Binodpur, Katihar,
Bihar - 854105
Mob : +91-92 34 34 4301
