The quadruple marker test is also known as the maternal serum test. Quadruple Marker Test is a blood test that provides useful information about the foetus. It helps estimate if a baby has an increased risk of having down syndrome, trisomy 18, neural tube defects or abdominal wall defects. The quadruple marker test results help predict the risk of such birth defects. However, it is also important to know that regardless of whether the quadruple marker test shows a low or high risk, it does not mean that the baby has a defect, but only indicated increased chances of the same. The name of the test comes from the fact that it measures the levels of four hormones that are found in all pregnant women’s blood namely:
Alpha-fetoprotein (AFP): A protein produced by the developing baby.
Human Chorionic Gonadotropin: A protein produced the placenta.
Estriol: Hormone produced by the placenta and baby’s liver.
Inhibin: Hormone produced by the placenta.
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CThe quadruple marker test measures four distinct proteins and hormones during pregnancy, hence it is also called the quad test at times. The high and low levels of these proteins and hormones depict the risk of birth defects in the developing foetus and provide useful information to a doctor for them to be able to prescribe further screening, if the need arises. The quadruple marker test measures the following four factors:
Alpha-fetoprotein (AFP)
Human Chorionic Gonadotropin
Estriol
Inhibin
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In pregnancy, a quadruple marker test is performed during the second trimester which ideally means sometime between 15 weeks and 20 weeks of pregnancy.
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Who may need Quadruple Maker Test ?
A Quadruple Marker Test may be recommended by the gynecologist for the following females:
Is above the age of 35 or older when the baby is due.
Has had a viral infection during pregnancy.
Has a family history of birth defects or congenital disabilities.
Is diagnosed with type 1 diabetes during pregnancy.
On harmful medication during pregnancy.
Has been exposed to high levels of radiation.
Normal Quadruple Marker Report ?
A normal quad screen result means that the individual doesn’t have an increased risk of having a baby with birth defects. The healthcare provider may or may not recommend further screening tests depending on the development of the foetus and other factors.
Abnormal Quadruple Marker Report ?
Abnormal levels of certain hormones and proteins in the quad screening test do not ascertain that a baby may be suffering from neural tube defects or Down’s syndrome. A quadruple marker test for pregnant women, allows doctors to suggest further tests to provide useful information about associated risks and finalise a diagnosis.
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Mob : +91-92 34 34 4301
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Rajhata, Binodpur, Katihar,
Bihar - 854105
Mob : +91-92 34 34 4301
